The Use of Reference Materials In the Analysis of Medicinal Plant Raw Materials and Herbal Medicinal Products

The need to improve pharmacopoeial approaches the standardization of medicinal plant raw materials (MPRMs) and herbal products (HMPs), ensure implementation principle «cross-cutting» in series «medicinal material – phyto-substance product» determine relevance developing new, more rational analysis objects origin. purpose research was theoretical experimental substantiation use reference development assay procedures on example certain types based it from standpoint chemical composition, stability physicochemical properties biologically active compounds contained them. Assay substances carried out by high performance liquid chromatography (HPLC) using a Milichrome-6 chromatograph with spectrophotometric detector ultraviolet (UV-) region. UV spectra were recorded Specord 40 spectrophotometer. measurement results processed WinASPECT Microsoft Excel 2016 programs. As result research, for syringin bark Syringa vulgaris, rhizomes roots Eleutherococcus senticosus, rosavin salidroside Rhodiola rosea, arbutin leaves Arctostaphylos uva-ursi Vaccinium vitis-idaea, isosalipurposide flowers Helichrysum arenarium, amount anthracene derivatives fresh Aloe arborescens developed validated. Spectrophotometric methods determining phenylpropanoids terms eleutheroside B (syringin) MPRMs HMPs senticosus aralosides Aralia Manchurian introduced. Based data obtained, scientific rationale (Syringa vulgaris bark, roots), (Rhodiola rosea sum ammonium salts (Manchurian aralia root), (Arctostaphylos vitis-idaea leaves), mixtures aloins A (Aloe leaves) provided. concept systematic approach formulated.